Health Technology Brief

supporting sound, evidence-based decision making

HT Briefs are concise technology assessment reports that provide an overall evaluation of the potential clinical and economic impact of new technologies
that are in the early stages of dissemination or of existing technologies that are being used for new applications.

View a sampling of our HT Briefs.

coflex Interlaminar Stabilization Device (Paradigm Spine LLC) for Treatment of Lumbar Spinal Stenosis

September 21, 2018 Health Technology Brief

Health Problem: Lumbar spinal stenosis (LSS), characterized by reduced spinal canal dimensions and compressed neural elements in the lower back, is predominately caused by degenerative changes in the intervertebral discs, ligaments, and bone structures of the spine. Mobility and quality of life are substantially adversely affected. LSS is the most common reason for spinal surgery in persons > 60 years of age. Technology Description: The coflex device is a U-shaped implant manufactured from medical-grade titanium alloy designed to withstand a normal physiologic load in the spine. The device is a single-piece design with 2 pairs of serrated wings. This design allows...

Eversense Continuous Glucose Monitor for Maintaining Glycemic Control in Adults with Diabetes Mellitus

September 14, 2018 Health Technology Brief

Health Problem: Diabetes mellitus (DM or diabetes) is a chronic, progressive disease characterized by impaired metabolism of carbohydrates. This disorder manifests in 2 main forms: type 1 DM and type 2 DM. Diabetes is associated with a high incidence of vascular disease involving the large and small blood vessels, which contribute to late secondary complications of diabetes, including atherosclerotic heart disease, peripheral atherosclerotic disease, nephropathy, neuropathy, and retinopathy. Diabetes affects approximately 30 million Americans (9.4% of the population) and costs $327 billion annually in the United States. Management of DM involves monitoring blood glucose levels and treatment may include diet,...

FreeStyle Libre Flash Glucose Monitoring System for Maintaining Glycemic Control in Adults with Diabetes Mellitus

September 4, 2018 Health Technology Brief

Health Problem: Diabetes mellitus (DM or diabetes) is a chronic, progressive disease characterized by impaired metabolism of carbohydrates. This disorder manifests in 2 main forms: type 1 DM and type 2 DM. Type 1 DM typically manifests during childhood and adolescence but can also develop in adults. Type 1 DM accounts for < 10% of cases and stems from the lack of production of the hormone insulin resulting from autoimmune destruction of beta cells in the pancreas. In contrast, type 2 DM, which accounts for 90% of cases of diabetes, is a result of inadequate insulin secretion because patients have...

Photodynamic Therapy with Verteporfin (Visudyne) for Choroidal Hemangioma

August 29, 2018 Health Technology Brief

Health Problem: Choroidal hemangioma is a relatively uncommon benign vascular tumor that presents either as a circumscribed mass, generally without systemic associations, or as a diffuse mass that is often associated with Sturge-Weber syndrome. Choroidal hemangiomas can produce visual acuity loss from macular fluid or even lead to serous retinal detachment and elevated risk for neovascular glaucoma, necessitating enucleation. Technology Description: Photodynamic therapy (PDT) is a therapeutic technique that involves the use of a photosensitizing agent, such as verteporfin, that produces selective tissue damage when activated by light of a specific wavelength. Unlike other currently available treatments for choroidal hemangioma, PDT...

Partial Knee Arthroplasty with the Mako Robotic-Arm Assisted Surgery (Stryker) for Treatment of Osteoarthritis

August 22, 2018 Health Technology Brief

Health Problem: Osteoarthritis (OA) is a degenerative disorder affecting more than 30 million adults in the United States and is the leading cause of disability in older adults. OA is characterized by the breakdown of joint cartilage with involvement of the subchondral bone and synovium. Symptoms of OA of the knee include joint pain, stiffness, and swelling, which ultimately impact joint function and can lead to disability. The treatment goals for OA are pain relief, maintenance of joint flexibility, and optimizing joint function. Knee OA symptoms that are recalcitrant to conservative measures may be treated by intra-articular injections or surgically...