Health Technology Brief

supporting sound, evidence-based decision making

HT Briefs are concise technology assessment reports that provide an overall evaluation of the potential clinical and economic impact of new technologies
that are in the early stages of dissemination or of existing technologies that are being used for new applications.

View a sampling of our HT Briefs.

Stellate Ganglion Block for Treatment of Posttraumatic Stress Disorder

January 16, 2018 Health Technology Brief

Health Problem: Posttraumatic stress disorder (PTSD) is an anxiety disorder that develops after an individual experiences or witnesses actual or threatened death or serious injury to him/herself or someone else, and reacts to the event with a feeling of fear, helplessness, and/or horror. PTSD is a disruptive disorder that is associated with decreased job performance, increased prevalence of comorbid physical and mental health problems, substance abuse, poor quality of life, short- and long-term disability, increased suicide risk, and increased healthcare utilization. Technology Description: SGB is an injection of local anesthetic into the neck. SGB may reduce symptoms associated with PTSD, due...

Glucagon-Like Peptide-1 Receptor Agonists for the Treatment of Obesity in Women with Polycystic Ovary Syndrome

December 29, 2017 Health Technology Brief

Health Problem: Polycystic ovary syndrome (PCOS) is a common endocrine disorder affecting 6% to 20% of women of reproductive age. It is characterized by oligoovulation (menstrual irregularity), hyperandrogenism (increased testosterone levels), and polycystic ovaries. Obesity is a common feature of PCOS, affecting approximately 40% to 80% of women diagnosed with the syndrome. Weight loss is a central component of treatment for women with PCOS who are overweight or obese. Weight reduction can decrease androgen effects, increase ovulation, and improve insulin sensitivity. Technology Description: Glucagon-like Peptide-1(GLP-1) receptor agonists are a class of drugs that mimic the effects of the naturally occurring gut...

Teduglutide (Gattex; Shire-NPS Pharmaceuticals Inc.) to Reduce Parenteral Support Requirements in Adults with Short Bowel Syndrome

December 27, 2017 Health Technology Brief

Health Problem: Short bowel syndrome (SBS) is a rare malabsorptive condition in which the bowel is anatomically or functionally inadequate to meet absorptive nutritional needs. The goal of SBS therapy is to optimize enteral autonomy and reductions in parenteral support (PS) requirements, which is associated with morbidity, complications, reduced quality of life, and high cost. Technology Description: Teduglutide is a recombinant glucagon-like peptide (GLP-2) that is approved by the Food and Drug Administration for the treatment of adult patients with SBS who are dependent on PS. The once-daily dose of 0.05 milligram/kilogram is given subcutaneously in alternating sites in the abdomen...

Radiofrequency Nerve Ablation for Treatment of Plantar Fasciitis

December 14, 2017 Health Technology Brief

Health Problem: Plantar fasciitis (PF) is inflammation of the plantar fascia, the thick connective tissue that lies between the heel bone and the base of the toes. Repetitive microtrauma leads to degeneration and inflammation of the plantar fascia, which causes chronic heel pain. PF is the most common cause of heel pain and the reason for more than 1 million patient visits per year in the United States. PF is primarily treated nonoperatively, and up to 95% of patients have symptom resolution within 12 to 18 months. Technology Description: Radiofrequency nerve ablation (RFNA) is a minimally invasive procedure that has been...

Dorsal Root Ganglion Stimulation for the Treatment of Complex Regional Pain Syndrome

December 12, 2017 Health Technology Brief

Health Problem: Complex regional pain syndrome (CRPS) is characterized by ongoing evoked or spontaneous regional pain that is out of proportion to known trauma or other causative lesion and shows variable progression over time. Type I CRPS (formerly known as reflex sympathetic dystrophy [RSD]) typically occurs after an illness or injury that did not directly damage the affected area. Type II CRPS (formerly known as causalgia) typically follows a nerve injury. Technology Description: The DRG is considered to have a gatekeeper role in pain and has been the topic of investigation as an alternate anatomic target for neuromodulation as a more...