Health Technology Brief

supporting sound, evidence-based decision making

HT Briefs are concise technology assessment reports that provide an overall evaluation of the potential clinical and economic impact of new technologies
that are in the early stages of dissemination or of existing technologies that are being used for new applications.

View a sampling of our HT Briefs.

LUKE Arm (Mobius Bionics LLC) for Upper Extremity Amputation

May 10, 2018 Health Technology Brief

Health Problem: Amputation presents a significant disability that can have profound physical, psychological, and vocational consequences in a person’s life. Approximately 50,000 people undergo an amputation of the upper or lower limb each year in the United States, with upper limb amputations accounting for approximately 25% of these amputations. Technology Description: Developed by DEKA Research & Development Corporation through funding provided in part by the Defense Advanced Research Project Agency, the life under kinetic evolution (LUKE) arm is an upper limb prosthesis intended to restore limb function in individuals who have lost all or part of either upper limb. It is...

Tap Water Iontophoresis for the Treatment of Primary Hyperhidrosis

April 27, 2018 Health Technology Brief

Health Problem: Primary hyperhidrosis is defined as sweat production beyond what is physiologically necessary for the maintenance of thermal homeostasis without any discernible cause. The most common sites for involvement are the axillae, palms, and soles of the feet. Hyperhidrosis may have marked impact on ability to perform activities of daily living as well as quality of life, including employability, education, and social life. Technology Description: In tap water iontophoresis (TWI), the palms of the hands and/or soles of the feet are immersed in a tray of tap water through which a weak electrical current is run. Sponges soaked in water...

Absorbable Perirectal Spacer (SpaceOAR System; Augmenix Inc.) During Radiation Therapy for Prostate Cancer

April 10, 2018 Health Technology Brief

Health Problem: The National Cancer Institute estimates 161,360 new cases of prostate cancer (PCa) in 2017 and 26,730 deaths. Technology Description: The SpaceOAR absorbable perirectal spacer (APS) is a polyethylene glycol hydrogel that is injected under anesthesia with transrectal ultrasound guidance into a space between the prostate and rectum. The APS is injected via dual syringes attached to a Y connector to allow for the 2 precursor agents to mix while being injected. The APS polymerizes into a solid spacer within 10 seconds following injection and is said to maintain its structure for 3 months before it starts to slowly...

Liraglutide (Saxenda) For Weight Loss in Nondiabetic Obese Adults

March 29, 2018 Health Technology Brief

Health Problem: The prevalence of obesity remains high in the United States. Recent estimates indicate that more than one-third of adults have obesity. Obesity is a serious health concern because it adversely affects mental health and quality of life, and is associated with leading causes of death, including diabetes, heart disease, stroke and some types of cancer. Technology Description: Liraglutide is a glucagon-like peptide-1 (GLP-1) receptor agonist. GLP-1 receptor agonists are a class of drugs that mimic the effects of the naturally occurring gut hormone GLP-1. The GLP-1 hormone, which is released in the gastrointestinal tract after a meal, stimulates insulin...

Laser Therapy Using MonaLisa Touch (Cynosure Inc.) for Vulvovaginal Atrophy

March 28, 2018 Health Technology Brief

Health Problem: Vulvovaginal atrophy, also known as atrophic vaginitis or genitourinary syndrome of menopause, is a collection of signs and symptoms that are caused by changes to the urogenital tissues due to a decrease in estrogen and other sex steroids. Effects of vulvovaginal atrophy include sexual and urinary tract dysfunction, such as vaginal dryness, dyspareunia, and urinary incontinence. Vulvovaginal atrophy affects nearly 50% of postmenopausal women and also develops in other women who have reduced levels of circulating estrogen. It is a chronic and progressive disorder that is associated with reduced quality of life. Vulvovaginal atrophy is treated with over-the-counter...