Health Technology Brief

supporting sound, evidence-based decision making

HT Briefs are concise technology assessment reports that provide an overall evaluation of the potential clinical and economic impact of new technologies
that are in the early stages of dissemination or of existing technologies that are being used for new applications.

View a sampling of our HT Briefs.

Impella CP (Abiomed) for Use in Adult Patients with Cardiogenic Shock

August 31, 2017 Health Technology Brief

Cardiogenic shock (CS) is an acute life-threatening condition resulting from inadequate blood circulation due to the inability of the heart (most often the left ventricle) to adequately meet systemic tissue demands for oxygen and nutrients. Technology Description: The Impella CP is an intravascular nonpulsatile axial blood pump designed to support the circulatory system during CS, low output syndrome, or other conditions. Typically, it is inserted percutaneously through the femoral artery and threaded into the left ventricle where it pumps blood from the left ventricle into the aorta. The Impella CP has a 14 Fr diameter and pumps at a rate of...

Propel and Propel Mini Bioabsorbable Steroid-Releasing Sinus Implants for Treatment of Chronic Rhinosinusitis in Adults

August 24, 2017 Health Technology Brief

Sinusitis is an inflammation of the nasal cavity and paranasal sinuses that is estimated to affect 13% to 15% of adults in the United States, resulting in more than 30 million annual diagnoses. Technology Description: The Propel and Propel Mini sinus devices are self-expanding bioabsorbable stents formed of a synthetic polymer (L-lactide-co-glycolide) in a lattice pattern. Mometasone furoate (MF) is a topical synthetic corticosteroid with activity against nasal symptoms. Both Propel stents are coated with 370 micrograms (µg) of MF that is released locally to the mucosa over a 30-day period. The stents are placed via a proprietary endoscopic system in...

Noncontact Low-Frequency Ultrasound Using the MIST Therapy System (Celleration Inc.) for Treatment of Venous Leg Ulcers

August 3, 2017 Health Technology Brief

The publication date for this report is June 30, 2016. A typographical error was corrected on August 3, 2017. See Publication History in the full report for details. Description of Technology The MIST Therapy System is a noncontact, low-frequency ultrasound debridement device that promotes healing of chronic wounds by removing yellow slough, tissue exudates, fibrin, and bacteria from the wound surface. The main components of the MIST Therapy System are an ultrasound generator; a hand-held ultrasound transducer; and a single-use, disposable applicator with a bottle reservoir for sterile saline. The transducer tip vibrates 40,000 times per second to generate ultrasound waves at...

Bielfeld Eustachian Tube Balloon Dilation for the Treatment of Chronic Eustachian Tube Dysfunction in Adults

July 20, 2017 Health Technology Brief

Eustachian tube dysfunction (ETD) is the inability of the eustachian tube (ET) to ventilate the middle ear, drain secretions, or protect the middle ear from sounds or pathogens in the nasopharynx. ETD is associated with otologic and rhinology symptoms, including tinnitus (ringing in the ears), aural fullness, an inability to equilibrate middle ear pressure, a sensation of being underwater, impaired hearing, pain, and balance problems. Description of Technology: This health technology assessment focuses on ET balloon dilation (ETBD) with the Bielefeld balloon catheter, which is also referred to as the Bielefelder Ballonkatheter, Bielfeld, Bielefeld device, BET-Catheter, or, most recently, TubaVent balloon...

Acclarent Eustachian Tube Balloon Dilation for the Treatment of Eustachian Tube Dysfunction in Adults

July 13, 2017 Health Technology Brief

Eustachian tube dysfunction (ETD) is the inability of the eustachian tube (ET) to ventilate the middle ear, drain secretions, or protect the middle ear from sounds or pathogens in the nasopharynx. ETD is associated with otologic and rhinology symptoms, including tinnitus (ringing in the ears), aural fullness, an inability to equilibrate middle ear pressure, a sensation of being underwater, impaired hearing, pain, and balance problems. Description of Technology: The Aera Eustachian Tube Balloon Dilation (ETBD) System is the first balloon device approved for ETD in the United States. The Aera device consists of a guidance catheter and a 16 × 6...