Medical Technology Directory

health technology evaluations at your fingertips

Hayes Medical Technology Directory is a comprehensive collection of in-depth health technology assessment reports designed to support evidence-based policies, guideline development, and technology acquisition. Below is a brief sampling of our Directory publications.

View a sampling of our Directory reports.

Comparative Effectiveness of Skin Substitutes for Chronic Venous Leg Ulcers in Adults: A Review of Reviews

November 16, 2017 Medical Technology Directory

Health Problem: Venous leg ulcers, also known as venous stasis ulcers or varicose ulcers, are partial or full-thickness defects in the skin of the lower leg, typically between the knee and the ankle, caused by venous hypertension as a result of valvular incompetence and venous reflux. These wounds impair function and quality of life, and chronic venous leg ulcers are susceptible to infection. Technology Description: Skin substitutes are proposed as a treatment to cover open chronic venous ulcers and promote wound healing, with the goals of improving quality of life and preventing further morbidity such as infection. They are thought to...

Functional Electrical Stimulation for Rehabilitation Following Spinal Cord Injury

November 16, 2017 Medical Technology Directory

Health Problem: Spinal cord injury (SCI) is typically the result of trauma. Automobile accidents are the most common cause, with falls and violence (primarily gunshot wounds) next in frequency. Various studies of the prevalence of SCI in the United States for the year 2016 have reported estimates between 243,000 and 347,000 persons. Although SCI used to occur primarily in young adults, the current average age at injury is 42.0 years. Cases are reported predominately in men (80%). Technology Description: Functional electrical stimulation (FES) is the direct application of safe levels of electric current to intact nerve fibers in a coordinated fashion...

Comparative Effectiveness Review of Platelet-Rich Plasma for Treatment of Lateral Epicondylitis: A Review of Reviews

November 14, 2017 Medical Technology Directory

Health Problem: Forearm pain that arises from overuse of the wrist extensor muscles may be due to tendon damage at the lateral epicondyle, a condition known as lateral epicondylitis (LE) or tennis elbow. LE is a common condition that affects 1% to 3% of adults each year. Technology Description: Platelet-rich plasma (PRP) is blood plasma with a higher-than-usual concentration of platelets. The injection of autologous PRP is proposed to improve local healing, thereby treating conditions, including LE. Controversy: PRP preparations are not standardized and exhibit wide variability in platelet and white blood cell concentrations and the use of thrombin activators. How these...

Comparative Effectiveness Review of Platelet-Rich Plasma for Knee Osteoarthritis: A Review of Reviews

November 9, 2017 Medical Technology Directory

Health Problem: Osteoarthritis (OA) is a painful condition in which the cartilage between the bones degenerates, no longer providing a smooth, gliding surface for motion or adequate cushioning. Because OA damages the cartilage and may ultimately damage the bone, it disrupts how components work together, resulting in pain, swelling, inflammation, muscle weakness, impaired quality of life, and reduced function. The knee is commonly afflicted by OA. Technology Description: Platelet-rich plasma (PRP) is blood plasma with a higher-than-usual concentration of platelets. The intra-articular (IA) injection of autologous PRP is proposed to improve local healing, thereby treating conditions, including knee OA. Controversy: Some researchers...

Comparative Effectiveness of Skin Substitutes for Chronic Foot Ulcers in Adults with Diabetes Mellitus: A Review of Reviews

November 9, 2017 Medical Technology Directory

Health Problem: Diabetes can damage blood vessels, compromising blood flow and oxygen circulation. Resulting tissue hypoxia may contribute to failure of even minor wounds to heal. Reasons are multifactorial and may include compromised sensation due to diabetes-related nerve damage and poor blood flow due to diabetes-related blood vessel damage. Technology Description: Skin substitutes are proposed as a treatment to cover open chronic ulcers and promote wound healing, with the goals of preventing infection and amputation. They are thought to function by physically covering the wound and providing extracellular matrices to induce regeneration and immune function. Skin substitutes, also known as bioengineered,...