Medical Technology Directory

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Hayes Medical Technology Directory is a comprehensive collection of in-depth health technology assessment reports designed to support evidence-based policies, guideline development, and technology acquisition. Below is a brief sampling of our Directory publications.

View a sampling of our Directory reports.

Autologous Hematopoietic Stem Cell Transplantation for the Treatment of Systemic Sclerosis

July 19, 2019 Medical Technology Directory

Health Problem: Systemic sclerosis (SSc) is a progressively disabling autoimmune disease of the connective tissue that causes skin thickening; the disease can thicken visceral connective tissue that results in organ impairment, organ failure, and mortality. SSc is a rare disease, estimated to affect 250 people per 1,000,000 population in the United States. Technology Description: During hematopoietic stem cell transplantation (HSCT), a patient undergoes a partially or fully myeloablative conditioning regimen, followed by infusion of autologous or allogenic hematopoietic stem cells. The goal of HSCT for SSc is to eradicate the dysfunctional immune cells mediating the disease and enable the formation of...

Comparative Effectiveness Review of Hybrid Maze Procedure for Atrial Fibrillation

July 15, 2019 Medical Technology Directory

Health Problem: Atrial fibrillation (AF) is a supraventricular, accelerated heart rhythm characterized by uncoordinated atrial activation that leads to inefficient, irregular atrial contraction. According to 2010 data, approximately 2.7 to 6.1 million people in the United States have AF. In both men and women, AF is associated with a significantly increased risk of death, stroke, declining cognitive function, and development of dementia. Technology Description: The hybrid maze (HM) procedure, also referred to as hybrid ablation or a convergent procedure, combines 2 minimally invasive procedures, surgical ablation (SA) and catheter ablation (CA), for treatment of AF. SA involves an epicardial approach whereas...

Endolumenal Functional Lumen Imaging Probe (EndoFLIP; Medtronic Inc.) for Evaluation of Esophageal and Gastric Disorders

June 14, 2019 Medical Technology Directory

Health Problem: The esophageal and gastric disorders most frequently evaluated with the Endolumenal Functional Lumen Imaging Probe (EndoFLIP) are achalasia, eosinophilic esophagitis (EE), and gastroparesis, but these disorders are relatively rare, with prevalence ranging from approximately 11 to 52 cases per 100,000 persons in the general population. Disorders of esophageal motility can cause symptoms such as impaction of food at the base of the esophagus, leading to pain and regurgitation. Similarly, disorders of gastric motility can cause delayed stomach emptying, leading to bloating, pain, nausea, and vomiting. Technology Description: During use, the EndoFLIP catheter extends from the esophagus into the stomach or from...

Platelet-Rich Plasma for Hip Osteoarthritis

June 14, 2019 Medical Technology Directory

Health Problem: Osteoarthritis (OA) is a painful condition that occurs when the cartilage between the bones degenerates, no longer providing a smooth, gliding surface for motion or adequate cushioning. Damaged articular cartilage does not tend to heal and may progressively worsen and cause focal lesions and eventually OA. Hip OA is common. The estimated lifetime risk for symptomatic hip OA is 18.5% for men and 28.6% for women. Technology Description: Platelet-rich plasma (PRP) is an autologous blood preparation with a higher-than-usual concentration of platelets, platelet-derived growth factor, and other cytokines. PRP preparation protocols vary considerably but always entail centrifugation of whole blood obtained...

Comparative Effectiveness Review of Radioactive Yttrium-90 Microspheres for Treatment of Primary Unresectable Liver Cancer

June 11, 2019 Medical Technology Directory

Health Problem: Hepatocellular carcinoma (HCC) is the most common liver malignancy in the United States, accounting for approximately 90% of primary liver cancers. The definitive therapies for HCC are surgical resection, tumor ablation, and liver transplantation; however, most patients are not eligible for these therapies due to the overall burden or severity of their disease. As a result, patients require a range of locoregional and systemic therapies for HCC that is not amenable to curative approaches. Technology Description: Transarterial radioembolization (TARE) with yttrium-90 (90Y) microspheres is an alternative treatment option that allows for much higher doses of radiation to be delivered to the...