Medical Technology Directory

health technology evaluations at your fingertips

Hayes Medical Technology Directory is a comprehensive collection of in-depth health technology assessment reports designed to support evidence-based policies, guideline development, and technology acquisition. Below is a brief sampling of our Directory publications.

View a sampling of our Directory reports.

Percutaneous Mechanical Thrombectomy and Ultrasound-Assisted Thrombolysis for Pulmonary Embolism

June 19, 2018 Medical Technology Directory

Health Problem: Venous thromboembolism (VTE) occurs when a blood clot blocks blood circulation and pulmonary embolism (PE) occurs when a blood clot dislodges and travels into pulmonary circulation. PE causes serious morbidity and mortality, with a 1-month mortality rate of 12%. Technology Description: Percutaneous mechanical thrombectomy (PMT) and ultrasound-assisted thrombolysis (UAT) involve the mechanical or ultrasound-facilitated removal of a thrombus or embolism from the venous system using percutaneous access. PMT and UAT devices utilize various mechanisms to disrupt and remove thromboembolisms, including rheolytic, rotational, and ultrasound-assisted systems. PMT and UAT are often used in concert with local application of thrombolytic drugs. Controversy: PMT...

Comparative Effectiveness Review of Choline PET or Choline PET-CT for Recurrent Prostate Cancer

June 14, 2018 Medical Technology Directory

Health Problem: Prostate cancer is the most common cancer diagnosis and the second leading cause of cancer-related deaths in men in the United States. Within 10 years of successful treatment for localized prostate cancer, serum prostate specific antigen (PSA) levels will rise to detectable levels in approximately 15% to 40% of men. Most often, a rising PSA is an indication of prostate cancer recurrence, although uncommonly this phenomenon may be a benign PSA-only relapse due to residual normal prostate tissue after surgery or radiation. Technology Description: Choline is a molecule involved in the synthesis of the structural components of cell membrane...

Comparative Effectiveness Review of Fluciclovine PET-CT or Prostate-Specific Membrane Antigen (PSMA) PET-CT for Recurrent Prostate Cancer

June 7, 2018 Medical Technology Directory

Health Problem: Prostate cancer is the most common cancer diagnosis and the second leading cause of cancer-related deaths in men in the United States. Within 10 years of successful treatment for localized prostate cancer, serum prostate specific antigen (PSA) levels will rise to detectable levels in approximately 15% to 40% of men. Most often, a rising PSA is an indication of prostate cancer recurrence, although uncommonly this phenomenon may be a benign PSA-only relapse due to residual normal prostate tissue after surgery and/or radiation. Technology Description: For fluciclovine positron emission tomography-computed tomography (PET-CT) and prostate-specific membrane antigen (PSMA) ligand PET-CT, patients...

Comparative Effectiveness Review of Transcatheter Closure of Patent Foramen Ovale for Prevention of Recurrent Cryptogenic Stroke

May 31, 2018 Medical Technology Directory

Health Problem: A patent foramen ovale (PFO) is a persistent, flap-like opening between the atrial septum primum and secundum. In 25% of adults, the foramen ovale remains open, or patent. The presence of a PFO has no therapeutic consequence in otherwise healthy adults; however, right-to-left shunting can generate thrombus, with the potential for embolism to the brain or coronary arteries causing stroke or transient ischemic attack (TIA). Technology Description: Transcatheter occlusion with a permanently implanted device has been proposed as an alternative or addition to long-term anticoagulant therapy for the treatment of PFOs associated with cryptogenic stroke. Controversy: Since a direct association...

Comparative Effectiveness Review of Platelet-Rich Plasma for Rotator Cuff Repairs, Tendinopathies, and Related Conditions: A Review of Reviews

May 31, 2018 Medical Technology Directory

Health Problem: Tears and/or tendinopathy of the rotator cuff (RC) can occur due to degeneration, trauma, repetitive overhead motions, and/or excessive loading. Current treatment strategies generally do not restore the native functional and structural properties of the ligament or tendon due to the poor intrinsic healing response of those tissues. Technology Description: Platelet-rich plasma (PRP) is an autologous blood preparation with a high platelet concentration and with concentrated platelet-derived growth factors, which may be the primary contributors to the benefits of PRP therapy. Administration of PRP aims to introduce growth and reparative factors directly to the site of degeneration in order...