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Palynziq (Pegvaliase-pqpz) for Phenylketonuria

January 25, 2019

Palynziq is a subcutaneously administered replacement enzyme indicated to reduce blood phenylalanine concentrations in adult patients with phenylketonuria (PKU) who have uncontrolled blood phenylalanine concentrations greater than 600 micromoles per liter on existing management. Palynziq is the first FDA-approved enzyme substitution therapy to target the underlying cause of PKU.