Health Technology Assessments

Health Technology Assessments (HTAs) are a comprehensive systematic review and critical analysis of available evidence for A SINGLE medical technology for which there are several published clinical trials and a substantial body of evidence. This report details an entire technology class for which there are one or more indications or patient populations in use.

Our analysts evaluate clinical trial data, along with information regarding safety issues, coverage policies from the private and public sectors, regulatory approvals, consensus statements, and an overall projection of the potential clinical efficacy and economic impact of the technology. Reports are reviewed annually up to 5 years post publication to determine if there is new literature or evidence that would impact a change in rating and warrant an updated report.

Minimally Invasive Lumbar Decompression Device Kit (Vertos Medical Inc.) for Treatment of Lumbar Spinal Stenosis

Focus of the Report: The focus of this Health Technology Assessment is to evaluate the effectiveness and safety of the minimally invasive lumbar decompression (mild) procedure, an approach that uses a proprietary surgical kit (mild; Vertos Medical Inc.) to treat lumbar spinal stenosis (LSS) in adult (≥ 18 years old) patients.

Theta Burst Stimulation for Treatment-Resistant Unipolar Depression in Adults

Focus of the Report: The focus of this Health Technology Assessment (HTA) is to evaluate the effectiveness and safety of theta burst stimulation (TBS), alone and compared with repetitive transcranial magnetic stimulation (rTMS) and/or with sham TBS, for the management of treatment-resistant major depressive disorder (MDD) (unipolar treatment-…

Trabecular Bone Score to Predict Fracture Risk in Postmenopausal Patients

Focus of the Report: The focus of this Health Technology Assessment is evaluation of the effectiveness and safety of the trabecular bone score (TBS) as an adjunct to bone mineral density (BMD) measurement and/or other validated tools incorporating patient information for prediction of fracture risk and guidance of preventive treatment in post…

Mako Robotic-Arm (Stryker Corp.) Assisted Total Knee Arthroplasty

Focus of the Report: The focus of this Health Technology Assessment (HTA) is to evaluate the effectiveness and safety of the Mako Robotic-Arm assisted total knee arthroplasty (RATKA) system (Stryker) compared with manual total knee arthroplasty (TKA) for the treatment of knee osteoarthritis (KOA).

Conventional Radiofrequency Ablation for Sacroiliac Joint Denervation for Chronic Low Back Pain

Focus of the Report: The focus of this Health Technology Assessment (HTA) is to evaluate the effectiveness and safety of conventional (i.e., continuous, thermal) radiofrequency ablation (RFA) for sacroiliac joint (SIJ) denervation for the treatment of chronic low back pain (CLBP) thought to arise from the SIJ.

Proton Beam Therapy for Esophageal Squamous Cell Carcinoma

Focus of the Report: The focus of this Health Technology Assessment (HTA) is to evaluate the effectiveness and safety of proton beam therapy (PBT) compared with conventional (photon-based) external beam radiation therapies to treat esophageal squamous cell carcinoma (ESCC) in adults.

Technolo…

Proton Beam Therapy for Esophageal Adenocarcinoma

Focus of the Report: The focus of this Health Technology Assessment (HTA) is the evaluation of the effectiveness and safety of proton beam therapy (PBT) compared with conventional (photon-based) external beam radiation therapies for the treatment of esophageal adenocarcinoma (EAC) in adults.

Proton Beam Therapy for Treatment of Breast Cancer

Focus of the Report: The focus of this Health Technology Assessment (HTA) is to evaluate the safety and effectiveness of proton beam therapy (PBT) for the treatment of breast cancer with no distant metastasis. This HTA also compares the safety and effectiveness of PBT with conventional radiation therapies.