Genetic Test Evaluation

understanding how genetic tests impact patient management

The Genetic Test Evaluation program is a compilation of evidence-based assessments of genetic tests that provide clinicians with a clear,
objective view of the science behind genetic tests, the clinical evidence supporting them, and the use of these tests in clinical practice.

View a sampling of our GTE program.

Macula Risk PGx (ArcticDx Inc.)

January 9, 2019 Genetic Test Evaluation

A synopsis of the Macula Risk PGx test, a genetic prognostic and pharmacogenomics assay that assess patient risk for progression to advanced age-related macular degeneration.

Genetic Testing for Factor V Leiden in Women with Unexplained Recurrent Pregnancy Loss

December 19, 2018 Genetic Test Evaluation

This report evaluates the clinical utility of factor V Leiden mutation genetic testing in women with unexplained recurrent pregnancy loss.

Guardant360 (Guardant Health Inc.)

December 11, 2018 Genetic Test Evaluation

Guardant360 is a liquid biopsy noninvasive blood screen used to identify actionable alterations across all solid tumor sites and provide a report, which identifies Food and Drug Administration (FDA)-approved treatments and clinical trials to help guide treatment decisions. The focus of this review is to assess the evidence that supports the use of Guardant360 as a decision-making tool, which identifies potentially actionable genetic mutations to help guide treatment options. 

Genetic Testing for Individuals Clinically Diagnosed with Catecholaminergic Polymorphic Ventricular Tachycardia

December 11, 2018 Genetic Test Evaluation

This report evaluates the clinical utility of genetic testing for catecholaminergic polymorphic ventricular tachycardia (CPVT) in individuals clinically diagnosed (defined as eliciting atrial arrhythmias and bidirectional or polymorphic ventricular tachycardia by stress test) with CPVT for management of the disorder leading to improved health outcomes. 

Genetic Testing for Family Members of Individuals with Catecholaminergic Polymorphic Ventricular Tachycardia

December 11, 2018 Genetic Test Evaluation

This report evaluates the clinical utility of genetic testing in family members of individuals with catecholaminergic polymorphic ventricular tachycardia (CPVT). See Genetic Testing for Individuals Clinically Diagnosed with Catecholaminergic Polymorphic Ventricular Tachycardia report for individuals clinically diagnosed with CPVT.