The dNerva Lung Denervation System (Nuvaira Inc.) is an investigational, bronchoscopic catheter-based pulmonary nerve ablation system proposed to reduce the frequency and severity of chronic obstructive pulmonary disease (COPD) exacerbations.
Publications
Hayes Publications are available through the Hayes Knowledge Center, a portal to world-class research and unbiased analyses on the clinical, financial, and risk impacts of emerging, controversial, and disruptive healthcare technologies.Every Hayes publication is developed by multidisciplinary teams of clinicians and scientists using rigorous methods grounded in internally recognized standards for systematic review and Health Technology Assessment. Learn more about these evidence resources and see sample titles below.
See below for some of our recent publications.
Afamitresgene Autoleucel (Adaptimmune Therapeutics) for Advanced Synovial Sarcoma
Afamitresgene autoleucel is an investigational autologous engineered T-cell therapy for the treatment of HLA-A*02 positive patients with advanced synovial sarcoma expressing the MAGE-A4 antigen.
aXess Vascular Conduit (Xeltis) for Dialysis Access
The aXess graft (Xeltis) is a synthetic bioresorbable vascular conduit under investigation to establish arteriovenous access for hemodialysis in patients with end-stage renal disease.
Prademagene Zamikeracel (Abeona Therapeutics Inc.) for Recessive Dystrophic Epidermolysis Bullosa
Prademagene zamikeracel (pz-cel; formerly EB-101) (Abeona Therapeutics Inc.) is a gene-corrected epidermal sheet under investigation for the treatment recessive dystrophic epidermolysis bullosa.
CYB003 (Cybin Inc.) Deuterated Psilocybin Analogue for Major Depressive Disorder
CYB003 (Cybin Inc.) is an oral deuterated psilocybin analogue proposed for use in conjunction with supportive psychotherapy for treatment of patients with moderate to severe major depressive disorder who have had an inadequate response to an antidepressant medication.
FSYX Ocular Pressure Adjusting Pump (Balance Ophthalmics Inc.) for Open-Angle Glaucoma
The FSYX Ocular Pressure Adjusting Pump (Balance Ophthalmics Inc.) is an investigational negative pressure eye goggle intended for adjunctive therapy to reduce nocturnal intraocular pressure in patients with open-angle glaucoma and normal daytime intraocular pressure.
Fidanacogene Elaparvovec-dzkt (Beqvez; Pfizer Inc.) for Hemophilia B
Fidanacogene elaparvovec-dzkt (Beqvez; Pfizer Inc.) is a single-infusion gene therapy for the treatment of adults with moderate to severe hemophilia B who currently use factor IX prophylaxis therapy, or have current or historical life-threatening hemorrhage, or have repeated, serious spontaneous bleeding episodes, and do not have neutralizing antibodies to adeno-associated vi…
Ventura Interatrial Shunt (V-Wave Ltd.) for Heart Failure
The Ventura Interatrial Shunt (V-Wave Ltd.) is an investigational transcatheter interatrial shunt proposed for treatment of chronic heart failure.
Rusfertide (Protagonist Therapeutics Inc./Takeda Pharmaceutical Co. Ltd.) for Polycythemia Vera
Rusfertide (formerly PTG-300; Protagonist Therapeutics Inc./Takeda Pharmaceutical Co. Ltd.) is a subcutaneously injected hepcidin mimetic for the treatment of erythrocytosis associated with polycythemia vera.
Varipulse Pulsed Field Ablation (Biosense Webster Inc.) for Atrial Fibrillation
Varipulse is an investigational pulsed-field ablation system in development for treatment of paroxysmal atrial fibrillation.