Botaretigene sparoparvovec is an investigational gene replacement therapy for the treatment of X-linked retinitis pigmentosa due to mutations in the RPGR gene. It is administered by subretinal injection.
Publications
Researched and Curated by Clinical and Scientific Experts.Every Hayes clinical evidence report is developed by experienced teams that have been trusted by healthcare decision makers since 1989. Here is a sampling of our content that is being used every day to inform defensible, evidence-based decisions by payers and providers.
Not all reports are available for public preview. For more information, please contact us.
Donanemab for Alzheimer Disease
Donanemab is an investigational, intravenously administered amyloid beta-directed antibody proposed for the treatment of Alzheimer disease.
Laser Interstitial Thermal Therapy (LITT) for Treatment of Brain Radiation Necrosis
This report addresses whether full-text clinical studies, systematic reviews, and clinical practice guidelines and position statements support the use of laser interstitial thermal therapy (LITT), also known as stereotactic laser ablation (SLA), for the treatment of brain radiation necrosis (RN).
EndeavorRx (Akili Interactive Labs Inc.) for Treatment of Attention-Deficit/Hyperactivity Disorder in Children
This report addresses whether full-text clinical studies, systematic reviews, and clinical practice guidelines and position statements support the use of EndeavorRx (Akili Interactive Labs Inc.) to improve attention function in children with attention-deficit/hyperactivity disorder (ADHD).
Signatera (Natera Inc.)
This report evaluates the clinical validity and clinical utility of the Signatera test.
Amvuttra (Vutrisiran) for Polyneuropathy of Hereditary Transthyretin-Mediated Amyloidosis
Amvuttra (vutrisiran) is an injectable RNA interference (RNAi) therapeutic agent indicated for the treatment of the polyneuropathy of hereditary transthyretin-mediated amyloidosis in adults.
leva Pelvic Health System (Renovia Inc.) for Treatment of Urinary Incontinence
This report addresses whether full-text clinical studies, systematic reviews, and clinical practice guidelines and position statements support the use of the leva Pelvic Health System (Renovia Inc.) for the treatment of urinary incontinence (UI) in female patients.
VivAer (Aerin Medical Inc.) for Nasal Airway Remodeling to Treat Nasal Obstruction
This report addresses whether full-text clinical studies, systematic reviews, and clinical practice guidelines and position statements support the use of VivAer (Aerin Medical Inc.) for the treatment of nasal airway obstruction (NAO).
Laser Interstitial Thermal Therapy for Treatment of Recurrent Metastatic Brain Neoplasms
This report addresses whether full-text clinical studies, systematic reviews, and clinical practice guidelines and position statements support the use of laser interstitial thermal therapy (LITT), also known as stereotactic laser ablation (SLA), for the treatment of recurrent metastatic brain neoplasms.
Theta Burst Stimulation for Treatment-Resistant Unipolar Depression in Adults
Focus of the Report: The focus of this Health Technology Assessment (HTA) is to evaluate the effectiveness and safety of theta burst stimulation (TBS), alone and compared with repetitive transcranial magnetic stimulation (rTMS) and/or with sham TBS, for the management of treatment-resistant major depressive disorder (MDD) (unipolar treatment-…