Every Hayes clinical evidence report is developed by experienced teams that have been trusted by healthcare decision makers since 1989. Here is a sampling of our content that is being used every day to inform defensible, evidence-based decisions by payers and providers.
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Skysona (elivaldogene autotemcel; eli-cel) is lentiviral-based gene therapy indicated to slow the progression of neurologic dysfunction in boys 4-17 years of age with early, active cerebral adrenoleukodystrophy (CALD).
Focus of the Report: The focus of this Health Technology Assessment is to evaluate the safety and effectiveness of systemic hyperbaric oxygen therapy (HBOT) to treat adults with persistent post-concussive syndrome (PCS) after mild traumatic brain injury (mTBI).
Technology Description:…
This report addresses whether full-text clinical studies, systematic reviews, and clinical practice guidelines and position statements support the use of masculinizing voice and communication therapy for improvement in quality of life (QOL) or patient-reported measures of voice satisfaction or comfort, vocal skills, or voice masculinity for individuals with gender dysphoria (…
This report addresses whether full-text clinical studies, systematic reviews, and clinical practice guidelines and position statements support the use of the eCoin Peripheral Neurostimulator System in patients with urgency urinary incontinence (UUI).
This report addresses whether full-text clinical studies, systematic reviews, and clinical practice guidelines and position statements support the use of feminizing voice and communication therapy for improvement in quality of life (QOL) or patient-reported measures of voice satisfaction or comfort, vocal skills, or voice femininity for individuals with gender dysphoria (GD)….
Focus of the Report: The focus of this Health Technology Assessment (HTA) is to evaluate the safety and effectiveness of cyanoacrylate embolization (CAE) with the VenaSeal closure system (Medtronic Inc.) to treat symptomatic varicose veins. This HTA also compares the effectiveness and safety of the VenaSeal closure system with other endovenou…
The Vibrant vibrating capsule is an investigational device designed to alleviate symptoms of chronic idiopathic constipation (CIC) by inducing a bowel movement through mechanical vibration of the colon.
This report addresses whether full-text clinical studies, systematic reviews, and clinical practice guidelines and position statements support the use of the hybrid autologous chondrocyte implantation (ACI)/osteochondral autograft transfer system (OATS) procedure for treatment of osteochondral defects of the knee in adults. This report does not evaluate ACI or OATS as standal…
This report evaluates the analytical validity, clinical validity, and clinical utility of the PancraGEN (Interpace Diagnostics) test.
Focus of the Report: The focus of this Health Technology Assessment (HTA) is to evaluate the effectiveness and safety of magnetic sphincter augmentation (MSA) with the LINX Reflux Management System (Torax Medical Inc., acquired by Ethicon Inc.) for the treatment of gastroesophageal reflux disease (GERD).
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