This report evaluates the analytical validity, clinical validity, and clinical utility of the Oncotype DX AR-V7 Nucleus Detect test.
Oncotype DX AR-V7 Nucleus Detect (Epic Sciences)
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Publications
Researched and Curated by Clinical and Scientific Experts.Every Hayes clinical evidence report is developed by experienced teams that have been trusted by healthcare decision makers since 1989. Here is a sampling of our content that is being used every day to inform defensible, evidence-based decisions by payers and providers.
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Organ Care System Liver (OCS) Liver
The OCS Liver is a portable extracorporeal liver perfusion and monitoring system under investigation for the resuscitation, preservation, and assessment of liver allografts from donors after brain death or liver allografts from donors after circulatory death ≤ 55 years old in a near-physiologic, normothermic, and functioning state intended for a potential transplant recipient…
Retifanlimab for Squamous Cell Anal Cancer
Retifanlimab is an investigational intravenous humanized monoclonal antibody that inhibits the activity of programmed death-1 (PD-1). By blocking PD-1, retifanlimab acts as an immune checkpoint inhibitor, freeing T cells to kill cancer cells and boosting immune system response against certain cancers. Retifanlimab is proposed as a monotherapy for locally advanced and metastat…
Efgartigimod for Myasthenia Gravis
Efgartifimod is an investigational, intravenously administered neonatal Fc receptor antagonist in development for the treatment of generalized myasthenia gravis.
Tezepelumab for Severe, Uncontrolled Asthma
Tezepelumab is an investigational, subcutaneously injected, human monoclonal antibody that inhibits thymic stromal lymphopoietin. It is proposed for treatment of patients with severe, uncontrolled asthma.
Oleogel-S10 for Epidermolysis Bullosa
Oleogel-S10 is a semisolid gel containing 10% betulin-rich extract from birch bark and 90% refined sunflower oil. Betulin is a naturally occurring triterpene with medicinal properties believed to help modulate the inflammation response and encourage formation of new skin during wound healing. It is in development for the treatment of skin wounds associated with epidermolysis …
Triamcinolone Acetonide Extended-Release (Zilretta) for the Management of Knee Osteoarthritis
Focus of the Report: The use of Zilretta (triamcinolone acetonide extended-release injectable suspension) for the treatment of pain associated with knee osteoarthritis (KOA).
Technology Description: Zilretta (Flexion Therapeutics Inc.) is an extended-release intra-articular therapy for pat…
Kerendia (Finerenone) for Diabetic Kidney Disease
Kerendia (finerenone) is a nonsteroidal mineralocorticoid receptor antagonist indicated to reduce the risk of sustained estimated glomerular filtration rate (eGFR) decline, end stage kidney disease, cardiovascular death, non-fatal myocardial infarction, and hospitalization for heart failure in adult patients with chronic kidney disease associated with type 2 diabetes.
Aduhelm (Aducanumab) for Alzheimer Disease
Aduhelm (aducanumab) is an intravenously administered amyloid beta-directed antibody for the treatment of Alzheimer disease.
Avacopan for Anti-neutrophil Cytoplasmic Autoantibody-associated Vasculitis
Avacopan is an oral complement component 5a (C5a) antagonist for treatment of adult patients with anti-neutrophil cytoplasmic autoantibody (ANCA)-associated vasculitis (AAV).