Elivaldogene autotemcel (eli-cel) is a lentiviral-based gene therapy for treatment of childhood cerebral adrenoleukodystrophy (CALD).
Elivaldogene Autotemcel for Cerebral Adrenoleukodystrophy
read more
Publications
Researched and Curated by Clinical and Scientific Experts.Every Hayes clinical evidence report is developed by experienced teams that have been trusted by healthcare decision makers since 1989. Here is a sampling of our content that is being used every day to inform defensible, evidence-based decisions by payers and providers.
Not all reports are available for public preview. For more information, please contact us.
Betibeglogene Autotemcel for Beta Thalassemia
Betibeglogene autotemcel (beti-cel; brand name Zynteglo outside U.S.; formerly Lentiviral Autologous Beta-Globin Gene Therapy, LentiGlobin) aims to reduce or eliminate the need for regular blood transfusions in patients with transfusion-dependent beta thalassemia by replacing the faulty HBB gene in the patient’s DNA with a healthier copy of the …
Eko Artificial Intelligence-based Electrocardiography Low Ejection Fraction Tool Algorithm
The Eko artificial intelligence (AI)-based electrocardiography (ECG) low ejection fraction tool (ELEFT) algorithm is used with the Eko Duo + ECG Digital Stethoscope to analyze single-lead ECG data to detect low left ventricular ejection fraction (LVEF), and is proposed for point-of-care screening of adult patients in the primary care/outpatient setting.
Mahana IBS (Mahana Therapeutics Inc.) for Treatment of Irritable Bowel Syndrome
This report addresses whether full-text clinical studies, systematic reviews, and clinical practice guidelines and position statements support the use of Mahana IBS for irritable bowel syndrome (IBS) in adults to improve function and quality of life and lessen IBS symptom severity.
clonoSEQ (Adaptive Biotechnologies)
This report evaluates the analytical validity, clinical validity, and clinical utility of the clonoSEQ test (Adaptive Biotechnologies) specific to U.S. Food and Drug Administration (FDA)-cleared intended use.
MiVu Mucosal Integrity Testing (Diversatek Inc.) for Diagnosis of Gastroesophageal Reflux Disease in Adults
This report addresses whether full-text clinical studies, systematic reviews, and clinical practice guidelines and position statements support the use of MiVu Mucosal Integrity Testing System (Diversatek Inc.) as an adjunct to clinical endoscopy for the diagnosis of gastroesophageal reflux disease in adults.
Aduhelm (Aducanumab) for Early-Stage/Mild Alzheimer Disease
This report addresses whether full-text clinical studies, systematic reviews, and clinical practice guidelines and position statements support the use of aducanumab (Aduhelm; Biogen Inc.) for the treatment of patients with early-stage Alzheimer disease and mild cognitive symptoms.
Anumana Artificial Intelligence (AI)-based Electrocardiography (ECG) Algorithm for Detection of Low Left Ventricular Ejection Fraction (LVEF)
The Anumana artificial intelligence (AI)-based electrocardiography (ECG) algorithm analyzes 12-lead ECG data to detect low left ventricular ejection fraction (LVEF), and is proposed for detection of asymptomatic left ventricular systolic dysfunction (ALVSD) in adult patients in the primary care/outpatient setting.
Pegzilarginase for Arginase 1 Deficiency
Pegzilarginase is an investigational recombinant form of the human enzyme arginase 1 (ARG1) proposed for the treatment of pediatric and adult patients with ARG1 deficiency. It is administered by intravenous infusion or subcutaneous injection.
Amvuttra (Vutrisiran) for Polyneuropathy of Hereditary Transthyretin-Mediated Amyloidosis
Amvuttra (vutrisiran) is an injectable RNA interference (RNAi) therapeutic agent indicated for the treatment of the polyneuropathy of hereditary transthyretin-mediated amyloidosis in adults.