Researched and Curated by Clinical and Scientific Experts.

Every Hayes clinical evidence report is developed by experienced teams that have been trusted by healthcare decision makers since 1989. Here is a sampling of our content that is being used every day to inform defensible, evidence-based decisions by payers and providers.

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Remestemcel-L for Acute Graft-Versus-Host Disease

Remestemcel-L is an allogeneic liquid cell suspension of ex-vivo cultured adult human mesenchymal stem cells derived from healthy donor bone marrow proposed for the treatment of pediatric patients with acute graft-versus-host-disease (aGVHD) refractory to standard first-line steroid therapy.

Expandable Interbody Cages for Cervical Spinal Fusion

Focus of the Report: This Health Technology Assessment focuses on expandable interbody cages (EICs) for cervical fusion in patients with degenerative disc disease (DDD).

Technology Description: Interbody fusion procedures involve the removal of a pathologic disc and insertion of interbody cages and bone grafts, with the aim of stabilizing the spine by …

ColonSentry (Stage Zero Life Sciences)

The report evaluates the analytical validity, clinical validity, and clinical utility of the ColonSentry liquid biopsy test, a gene expression assay intended to estimate the current relative risk of having colorectal cancer (CRC) for patients eligible for CRC screening.

Botulinum Toxin for Treatment of Gastroparesis

Focus of the Report: Use of botulinum toxin (BTX) for treatment of gastroparesis.

Technology Description: BTX, a neurotoxin produced by the bacterium Clostridium botulinum, inhibits the release of the neurotransmitter acetylcholine at the neuromuscular junction and causes muscle paralysis. B…