Every Hayes clinical evidence report is developed by experienced teams that have been trusted by healthcare decision makers since 1989. Here is a sampling of our content that is being used every day to inform defensible, evidence-based decisions by payers and providers.
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Focus of the Report: This report focuses on the efficacy and safety of platelet-rich plasma (PRP) for treatment of venous leg ulcers (VLUs).
Technology Description: PRP is an autologous blood preparation with a higher-than-usual concentration of platelets, platelet-derived growth factors, and other cytokines. Protocols for PRP preparation vary consider…
Susvimo (ranibizumab injection) is a refillable ocular implant containing the vascular endothelial growth factor (VEGF) inhibitor ranibizumab indicated for the treatment of patients with neovascular (wet) age-related macular degeneration (AMD) who have previously responded to at least two intravitreal injections of a VEGF inhibitor.
Balstilimab is an investigational intravenous immunotherapy. It inhibits the activity of programmed death-1 (PD-1), an immune checkpoint protein that helps restrain the immune system. Balstilimab is proposed for the second-line treatment of advanced cervical cancer in patients with disease progression or who experience a relapse during or after chemotherapy.
Narsoplimab is an investigational, intravenous monoclonal antibody targeting mannan-binding lectin-associated serine protease-2 (MASP-2) for the treatment of hematopoietic stem cell transplant-associated thrombotic microangiopathy (HSCT-TMA).
The Lungpacer Diaphragm Pacing Therapy (DPT) system is a temporary, minimally invasive, transvenous phrenic nerve pacing system intended for treatment of patients on mechanical ventilation to facilitate weaning from the ventilator.
Focus of the Report: This report focuses on Rezūm water vapor therapy for the treatment of lower urinary tract symptoms (LUTS) in men with benign prostatic hyperplasia (BPH).
Technology Description: Rezūm is a minimally invasive surgical therapy that utilizes the convective principles …
Focus of the Report: The focus of this health technology assessment is use of the coflex Interlaminar Stabilization device (Surgalign Spine Technologies Inc.) for the treatment of lumbar spinal stenosis (LSS) in adults. The coflex device offers a minimally invasive adjunct to traditional decompressive surgery and a surgical alternative to spi…
Focus of the Report: This health technology assessment focuses on partial knee arthroplasty (PKA) with the Mako Robotic-Arm Assisted Surgery system for treatment of knee osteoarthritis (KOA).
Technology Description: The Mako Robotic-Arm system is a semi-active tactile robotic system, m…
Tavneos (avacopan) is an oral complement 5a receptor (C5aR) antagonist indicated as an adjunctive treatment of adult patients with severe active anti-neutrophil cytoplasmic autoantibody (ANCA)-associated vasculitis (granulomatosis with polyangiitis [GPA] and microscopic polyangiitis [MPA]) in combination with standard therapy including glucocorticoids.
The OCS Liver is a portable extracorporeal liver perfusion and monitoring system indicated for the preservation and monitoring of hemodynamics and metabolic function, which allows for ex-vivo assessment of liver allografts from donor-after-brain-death (DBD) and donor-after-circulatory-death (DCD) livers.