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Evidence Analysis
It is a challenge for health plans and clinicians to distill and analyze volumes of clinical evidence to determine likely clinical, financial, and risk impacts. This is what we do.Accessed through the Hayes Knowledge Center, the Evidence Analysis Solution addresses the following fundamental questions to help our clients determine coverage positions:
- Does the technology improve health outcomes?
- Are there other benefits associated with the technology?
- What harms might be associated with the technology?
- Have patient selection criteria been established for the technology?
- For which patients might the technology provide a benefit?
- Health Technology Assessments
- Evidence Analysis Research Briefs
- Comparative Effectiveness Review
- Clinical Research Responses
Tisagenlecleucel (Kymriah) for Treatment of Relapsed or Refractory CD19+ B-Cell Malignancies
Focus of the Report: This report evaluates the use of tisagenlecleucel (Kymriah) for the treatment of relapsed or refractory (r/r) B-cell acute lymphoblastic leukemia (ALL) or r/r diffuse large B-cell lymphoma (DLBCL).
Technology Description: Tisagenlecleucel therapy is a form of chime…
Genicular Nerve Block for the Management of Knee Pain
Focus of the Report: This health technology assessment focuses on the use of genicular nerve blocks (GNB) for the management of knee pain associated with osteoarthritis of the knee (KOA) or persistent pain following total knee arthroplasty (TKA).
Technology Description: In a GNB proced…
Electronic Monitoring Versus Direct Observation of Hand Hygiene Compliance in Healthcare Settings
Focus of the Report: This report focuses on electronic monitoring (EM) of hand hygiene (HH) in a hospital setting.
Technology Description: Electronic HH monitoring systems vary in their degree of sophistication. The simplest are straightforward counters that record the number of times …
Magnetic Resonance Elastography for Detecting and Staging Liver Fibrosis
Focus of the Report: This report focuses on magnetic resonance elastography (MRE) for diagnosis and staging of liver fibrosis.
Technology Description: MRE relies on visualization of the passage of sound waves through liver tissue while the patient is in a magnetic resonance imaging (MR…
Lymphovenous Anastomosis for the Physiological Microsurgical Treatment of Lymphedema
Focus of the Report: This report focuses on the use of lymphovenous anastomosis (LVA) for the surgical treatment of patients with lymphedema.
Technology Description: LVA is a microsurgical procedure used to restore adequate lymphatic drainage from tissues of the upper or lower extremit…
Prostatic Urethral Lift (UroLift System) for Treatment of Symptoms Associated with Benign Prostatic Hyperplasia
Focus of the Report: This health technology assessment focuses on prostatic urethral lift (PUL) with the UroLift System for treatment of lower urinary tract symptoms (LUTS) secondary to benign prostatic hyperplasia (BPH).
Technology Description: The UroLift System is a minimally invasi…
Expandable Interbody Cages for Cervical Spinal Fusion
Focus of the Report: This Health Technology Assessment focuses on expandable interbody cages (EICs) for cervical fusion in patients with degenerative disc disease (DDD).
Technology Description: Interbody fusion procedures involve the removal of a pathologic disc and insertion of interbody cages and bone grafts, with the aim of stabilizing the spine by …
Antibacterial Envelopes for the Prevention of Cardiac Implantable Electronic Device (CIED) Infections
Focus of the Report: This report focuses on the efficacy and safety of TYRX antibacterial envelopes (Medtronic Inc.) for the prevention of infection following implantation of cardiac implantable electronic devices (CIEDs).
Technology Description: The TYRX antibacterial envelope is a su…
Minimally Invasive Procedures for Thyroidectomy
Focus of the Report: This report focuses on minimally invasive techniques for thyroidectomy.
Technology Description: For minimally invasive thyroid surgery, patients are placed under general anesthesia and the procedure is performed through small incisions in the neck, breast, armpits,…