Accessed through the Hayes Knowledge Center, the Evidence Analysis Solution addresses the following fundamental questions to help our clients determine coverage positions:
Focus of the Report: This report focuses on the use of transcatheter mitral valve replacement (TMVR) for treating mitral regurgitation (MR), backward flow of blood due to a damaged or leaking mitral valve (MV) in the heart.
Technology Description: TMVR is a treatment for MR that uses percutaneous access through a peripheral artery to place a bioprosthe…
Focus of the Report: This report focuses on intradialytic parenteral nutrition (IDPN) for nutritional support in adults with end-stage renal disease (ESRD) who are undergoing hemodialysis.
Technology Description: IDPN is an intravenous infusion of essential nutrients administered durin…
Focus of the Report: The use of radiofrequency ablation (RFA) of the genicular nerves for the treatment of osteoarthritis of the knee (KOA).
Technology Description: In this report, RFA is defined as ablation of the peripheral nerves of the knee to relieve the pain associated with KOA. The …
Focus of the Report: This report focuses on the efficacy and safety of the 5-hydroxytryptamine 1F (5-HT1F) receptor agonist lasmiditan (Reyvow) for acute treatment of migraines.
Technology Description: The 5-HT1F receptors are…
Focus of the Report: This report focuses on the efficacy and safety of the calcitonin gene-related peptide (CGRP) receptor antagonist ubrogepant (Ubrelvy) for acute treatment of migraines.
Technology Description: Ubrogepant is approved for the acute treatment of migraine. Ubrogepant is a C…
Focus of the Report: This report evaluates the use of axicabtagene ciloleucel (Yescarta) for the treatment of relapsed or refractory (r/r) large B-cell lymphoma (LBCL).
Technology Description: Axicabtagene ciloleucel therapy is a form of chimeric antigen receptor (CAR) T-lymphocyte (T-…
Focus of the Report: This report focuses on fractional flow reserve (FFR), determined noninvasively via computed tomography (FFRCT), to detect coronary artery blockages, identified by coronary computed tomography angiography (CCTA), that may be responsible for myocardial ischemia in patients with known or suspected coronary artery disease (CA…
Focus of the Report: This report focuses on the use of the MitraClip Mitral Valve Repair System (Abbott Vascular Inc.) for treatment of secondary (or functional) mitral valve regurgitation (MR).
Technology Description: The MitraClip Mitral Valve Repair System is a minimally invasive d…
This report evaluates the analytical validity, clinical validity, and clinical utility of the ChemoFx test, an in vitro patient tumor–derived cell culture assay that determines how cancer cells may respond to chemotherapeutic agents in order to help guide physicians’ treatment decisions in patients with gynecologic cancer.
Focus of the Report: Transperineal template prostate (TTP) biopsy is an alternative to standard transrectal ultrasound (TRUS) biopsy for repeat biopsies. TTP biopsy is a form of saturation biopsy (at least 20 cores) that uses a brachytherapy grid to assure even distribution of the cores.
Tec…