Evidence Analysis

It is a challenge for health plans and clinicians to distill and analyze volumes of clinical evidence to determine likely clinical, financial, and risk impacts. This is what we do.

Accessed through the Hayes Knowledge Center, the Evidence Analysis Solution addresses the following fundamental questions to help our clients determine coverage positions:

  • Does the technology improve health outcomes?
  • Are there other benefits associated with the technology?
  • What harms might be associated with the technology?
  • Have patient selection criteria been established for the technology?
  • For which patients might the technology provide a benefit?

Masculinizing Voice and Communication Therapy for Gender Dysphoria

This report addresses whether full-text clinical studies, systematic reviews, and clinical practice guidelines and position statements support the use of masculinizing voice and communication therapy for improvement in quality of life (QOL) or patient-reported measures of voice satisfaction or comfort, vocal skills, or voice masculinity for individuals with gender dysphoria (…

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Cyanoacrylate Embolization With the VenaSeal Closure System (Medtronic Inc.) for the Treatment of Varicose Veins

Focus of the Report: The focus of this Health Technology Assessment (HTA) is to evaluate the safety and effectiveness of cyanoacrylate embolization (CAE) with the VenaSeal closure system (Medtronic Inc.) to treat symptomatic varicose veins. This HTA also compares the effectiveness and safety of the VenaSeal closure system with other endovenou…

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Hybrid Autologous Chondrocyte Implantation With Osteochondral Autograft Transfer System for Treatment of Osteochondral Defects of the Knee in Adults

This report addresses whether full-text clinical studies, systematic reviews, and clinical practice guidelines and position statements support the use of the hybrid autologous chondrocyte implantation (ACI)/osteochondral autograft transfer system (OATS) procedure for treatment of osteochondral defects of the knee in adults. This report does not evaluate ACI or OATS as standal…

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Wide-Area Transepithelial Sampling Biopsy for Detection of Barrett’s Esophagus/Esophageal Dysplasia

Focus of the Report: This Health Technology Assessment focuses on wide-area transepithelial sampling (WATS) biopsy with 3-dimensional (3D) imaging as an adjunct to or replacement for standard forceps biopsy of the esophagus for detection of Barrett’s esophagus (BE) and esophageal dysplasia, with the goal of reducing the risk of progression to…

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