Evidence Analysis

It is a challenge for health plans and clinicians to distill and analyze volumes of clinical evidence to determine likely clinical, financial, and risk impacts. This is what we do.

Accessed through the Hayes Knowledge Center, the Evidence Analysis Solution addresses the following fundamental questions to help our clients determine coverage positions:

  • Does the technology improve health outcomes?
  • Are there other benefits associated with the technology?
  • What harms might be associated with the technology?
  • Have patient selection criteria been established for the technology?
  • For which patients might the technology provide a benefit?
  • Clinical Research Responses

Allogeneic Hematopoietic Stem Cell Transplantation with Matched Unrelated Donors or Haploidentical Family Donors for Sickle Cell Disease in Pediatric Patients

Focus of the Report: The focus of this report is on allogeneic hematopoietic stem cell transplantation (HSCT) utilizing alternative human leukocyte antigen (HLA)-matched donor sources in pediatric patients with sickle cell disease (SCD) without an HLA-matched sibling donor (MSD).

Technology D…

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Coflex Interlaminar Stabilization Device (Surgalign Spine Technologies Inc.) for Treatment of Lumbar Spinal Stenosis

Focus of the Report: The focus of this health technology assessment is use of the coflex Interlaminar Stabilization device (Surgalign Spine Technologies Inc.) for the treatment of lumbar spinal stenosis (LSS) in adults. The coflex device offers a minimally invasive adjunct to traditional decompressive surgery and a surgical alternative to spi…

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