Evolving Evidence Reviews

Evolving Evidence Reviews are designed to help clients develop policies and manage prior authorizations. Evolving Evidence Reviews are useful when a technology moves beyond emerging but the literature is not mature enough for a full Health Technology Assessment. Evolving Evidence Reviews provide a full-text appraisal of clinical studies, systematic reviews, and clinical practice guidelines as they relate to a specific health technology. Evolving Evidence Reviews provide Levels of Support indicated by these types of evidence. They also provide information on regulatory status, payer policies, and Hayes Insights.

GraftJacket Now (Stryker) for Shoulder Surgeries

This report addresses whether full-text clinical studies, systematic reviews, and clinical practice guidelines and position statements support the use of GraftJacket and GraftJacket Now human dermal allografts (Stryker) during shoulder surgeries in adults.

GraftJacket Now (Stryker) for Hand Surgeries

This report addresses whether full-text clinical studies, systematic reviews, and clinical practice guidelines and position statements support the use of the GraftJacket Now human dermal allograft (Stryker) for hand surgeries in adults.

Gender-Affirming Hair Removal for Patients With Gender Dysphoria

This report addresses whether full-text clinical studies, systematic reviews, and clinical practice guidelines and position statements support gender-affirming hair removal (not related to gender-affirming surgery [GAS] preparation) for patients with gender dysphoria (GD).

Combination Facial Feminization Surgery in Patients With Gender Dysphoria

This report addresses whether full-text clinical studies, systematic reviews, and clinical practice guidelines and position statements support the use of facial feminization surgery (FFS)—i.e., multiple procedures in the head and/or neck regions combined in a single anesthesia session—for patients with gender dysphoria (GD).

Prolastin-C (Grifols Therapeutics Inc.) Compared With Other Augmentation Therapies for Management of Patients With Alpha-1 Antitrypsin Deficiency and Lung Disease

This report addresses whether full-text clinical studies, systematic reviews, and clinical practice guidelines and position statements support the use of alpha-1 antitrypsin (AAT) augmentation therapy with Prolastin or Prolastin-C over other alpha-1 proteinase inhibitors (A1PIs), for management of lung disease in patients with AAT deficiency (AATD).