This report addresses whether full-text clinical studies, systematic reviews, and clinical practice guidelines and position statements support the use of ENROUTE Transcarotid Stent with Neuroprotective System compared with open carotid endarterectomy (CEA) procedure for the treatment of coronary artery stenosis to improve clinical outcomes, decrease length of stay, and reduce complications. It is intended to provide updated information to the original report with the same title initially published October 6, 2020.