Focus of the Report: This report focuses on Rezūm water vapor therapy for the treatment of lower urinary tract symptoms (LUTS) in men with benign prostatic hyperplasia (BPH).

Technology Description: Rezūm is a minimally invasive surgical therapy that utilizes the convective principles of steam to trigger highly targeted necrosis of overgrown prostatic tissue, with the aim of reducing bladder outlet obstruction (BOO) and restoring patency to the urethral passageway.

Controversy: Rezūm water vapor thermal therapy (WVTT) represents a less invasive treatment option developed to reduce associated complications and preserve sexual function. However, questions remain regarding the durability of symptom relief and whether symptom relief from Rezūm WVTT is at least comparable to transurethral resection of the prostate.

Key Questions:

  • Is the Rezūm System effective for treatment of LUTS associated with BPH?

  • How does Rezūm water vapor therapy compare with surgical or other minimally invasive treatments for BPH?

  • Is Rezūm water vapor therapy safe?

  • Have definitive patient criteria been identified for the Rezūm system?

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