Noctiva is a low-dose desmopressin nasal spray proposed to treat adults with nocturia due to nocturnal polyuria.  Noctiva is a new formulation of an old drug which was first approved by the FDA in 1978 under the brand name DDAVP (Ferring Pharmaceuticals Inc.). Noctiva contains cyclopentadecanolide, an excipient that facilitates rapid absorption through the nasal mucosa and allows for use of lower doses of desmopressin to achieve a therapeutic effect.

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