Health Technology Assessments

Health Technology Assessments (HTAs) are a comprehensive systematic review and critical analysis of available evidence for A SINGLE medical technology for which there are several published clinical trials and a substantial body of evidence. This report details an entire technology class for which there are one or more indications or patient populations in use.

Our analysts evaluate clinical trial data, along with information regarding safety issues, coverage policies from the private and public sectors, regulatory approvals, consensus statements, and an overall projection of the potential clinical efficacy and economic impact of the technology. Reports are reviewed annually up to 5 years post publication to determine if there is new literature or evidence that would impact a change in rating and warrant an updated report.

Cyanoacrylate Embolization With the VenaSeal Closure System (Medtronic Inc.) for the Treatment of Varicose Veins

Focus of the Report: The focus of this Health Technology Assessment (HTA) is to evaluate the safety and effectiveness of cyanoacrylate embolization (CAE) with the VenaSeal closure system (Medtronic Inc.) to treat symptomatic varicose veins. This HTA also compares the effectiveness and safety of the VenaSeal closure system with other endovenou…

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Wide-Area Transepithelial Sampling Biopsy for Detection of Barrett’s Esophagus/Esophageal Dysplasia

Focus of the Report: This Health Technology Assessment focuses on wide-area transepithelial sampling (WATS) biopsy with 3-dimensional (3D) imaging as an adjunct to or replacement for standard forceps biopsy of the esophagus for detection of Barrett’s esophagus (BE) and esophageal dysplasia, with the goal of reducing the risk of progression to…

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Use of Anti-infliximab Antibody Levels to Monitor Infliximab Treatment in Patients With Crohn Disease

Focus of the Report: This Health Technology Assessment focuses on anti-infliximab (IFX) antibody (ATI) testing in patients who are undergoing IFX treatment for Crohn disease (CD). This testing is a type of therapeutic drug monitoring (TDM) that is performed to help determine whether ongoing treatment is safe and effective and whether changes …

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