Medical Technology Directory

health technology evaluations at your fingertips

Hayes Medical Technology Directory is a comprehensive collection of in-depth health technology assessment reports designed to support evidence-based policies, guideline development, and technology acquisition. Below is a brief sampling of our Directory publications.

View a sampling of our Directory reports.

Hematopoietic Stem Cell Transplantation for Treatment of Multiple Sclerosis

March 18, 2019 Medical Technology Directory

Health Problem: Multiple sclerosis (MS) is a potentially disabling autoimmune disease that impacts the central nervous system. MS is estimated to affect 400,000 to 1,000,000 people in the United States and 2,300,000 people worldwide. Technology Description: During hematopoietic stem cell transplantation (HSCT), a patient undergoes a partially or fully myeloablative conditioning regimen, followed by infusion of autologous or allogenic hematopoietic stem cells. The goal of HSCT for MS is to eradicate the dysfunctional immune cells mediating the disease and enable the formation of a more functional system using hematopoietic stem cells. Controversy: HSCT involves the administration of high levels of chemotherapeutic agents...

Comparative Effectiveness Review of Platelet-Rich Plasma for Treatment of Conditions of the Achilles Tendon and Plantar Fascia

March 14, 2019 Medical Technology Directory

Health Problem: Conditions of the Achilles tendon, such as Achilles tendon rupture (ATR) or Achilles tendinopathy (AT), as well as conditions of the plantar fascia (plantar fasciitis [PF]) can result from overuse or can be due to sports, age, and/or a combination of several factors. Technology Description: Platelet-rich plasma (PRP) is blood plasma with a higher-than-usual concentration of platelets. The injection of autologous PRP is proposed to improve local healing, thereby treating conditions, including ATR, AT, and PF. Controversy: PRP preparations are not standardized and exhibit wide variability in platelet and white blood cell concentrations, as well as the use of...

Comparative Effectiveness Review of Intensive Behavioral Intervention for Treatment of Autism Spectrum Disorder

March 13, 2019 Medical Technology Directory

Health Problem: Autism spectrum disorder (ASD) is a neurodevelopmental condition, which presents in childhood and is characterized by persistent deficits in social communication and social interaction; restricted, repetitive patterns of behavior, interests, or activities; and clinically significant impairment in social, occupational, or other important areas of current functioning. The estimated prevalence of ASD in 2014 was 1 in 59 among children 8 years of age. Technology Description: Intensive behavioral intervention (IBI) involves highly structured teaching techniques that are administered on an individual basis by a trained therapist, paraprofessional, and/or parent 15 to 40 hours per week for 2 to 3 years....

DaTscan (123I-Ioflupane; GE Healthcare) for Diagnosis and Management of Parkinson Disease

March 7, 2019 Medical Technology Directory

Health Problem: Parkinson disease (PD) is a neurodegenerative condition characterized by motor symptoms such as resting tremor, muscle rigidity, postural instability, and bradykinesia and nonmotor symptoms such as sleep disorders, olfactory impairment, attention/memory impairment, apathy, depression, and anxiety. The cause of PD is degeneration of the dopaminergic system due to loss of cells that produce dopamine in the substantia nigra of the brain. This degeneration leads to a marked loss of dopamine transporters (DaTs) and decline in dopamine-related brain functions such as control of movement. In the United States, PD currently affects > 1 million individuals and is newly diagnosed...

Transcranial Magnetic Stimulation for the Treatment of Obsessive-Compulsive Disorder

March 5, 2019 Medical Technology Directory

Health Problem: Obsessive-compulsive disorder (OCD) is a disorder characterized by intrusive obsessions and repetitive compulsions where symptoms interfere with a person’s routine, occupation, or social functioning; lifetime prevalence of OCD is estimated between 2% to 3% in the United States. Repetitive transcranial magnetic stimulation (rTMS) has been proposed as an alternative treatment for patients who are treatment resistant to 1 or more rounds of pharmacotherapy or behavioral therapy interventions for OCD. Technology Description: rTMS is a noninvasive technique that involves superficial but powerful magnetic stimulation of the brain. This is achieved by passing electrical energy through a round or figure-eight coil...