Health Technology Assessments

Health Technology Assessments (HTAs) are a comprehensive systematic review and critical analysis of available evidence for A SINGLE medical technology for which there are several published clinical trials and a substantial body of evidence. This report details an entire technology class for which there are one or more indications or patient populations in use.

Our analysts evaluate clinical trial data, along with information regarding safety issues, coverage policies from the private and public sectors, regulatory approvals, consensus statements, and an overall projection of the potential clinical efficacy and economic impact of the technology. Reports are reviewed annually up to 5 years post publication to determine if there is new literature or evidence that would impact a change in rating and warrant an updated report.

Platelet-Rich Plasma for Wound Treatment in Venous Leg Ulcers

Focus of the Report: This report focuses on the efficacy and safety of platelet-rich plasma (PRP) for treatment of venous leg ulcers (VLUs).

Technology Description: PRP is an autologous blood preparation with a higher-than-usual concentration of platelets, platelet-derived growth factors, and other cytokines. Protocols for PRP preparation vary consider…

Rezūm System (Boston Scientific Corp.) for Benign Prostatic Hyperplasia

Focus of the Report: This report focuses on Rezūm water vapor therapy for the treatment of lower urinary tract symptoms (LUTS) in men with benign prostatic hyperplasia (BPH).

Technology Description: Rezūm is a minimally invasive surgical therapy that utilizes the convective principles …

Fecal Microbiota Transplantation for the Treatment of Ulcerative Colitis

Focus of the Report: This report focuses on the use of fecal microbiota transplantation (FMT) to treat adults with ulcerative colitis (UC).

Technology Description: FMT is a procedure by which processed stool from healthy donors is infused into a patient’s gastrointestinal (GI) system for the purpose of treating a disease associated with impaired gut mi…